HS-LS3-2 | Sources of Genetic Variation

From NY Science Standards Wiki
← HS-LS3-1
HS-LS3-3 →

Make and defend a claim based on evidence that inheritable genetic variations may result from: (1) new genetic combinations through meiosis, (2) viable errors occurring during replication, (3) mutations caused by environmental factors and/or (4) genetic engineering.

Clarification statement: Emphasis is on using data to support arguments for the way variation occurs including the relevant processes in meiosis and advances in biotechnology.

Assessment boundary: Assessment does not include recalling the specific details of the phases of meiosis or the biochemical mechanisms of the specific phases in the process.

Assessment

What assessment of HS-LS3-2 might look like on a NY state exam.

Exam Cluster Question
August 2026 Human Variations in Eye Color Question 9
Humongous Fungus Question 15
Frog Development Question 27
June 2026 Tailless Humans Question 22
Caffeine’s Effect on the Body Question 40
January 2026 Two Kinds of Twins Question 3
Solving the Problem of Cat Allergies Question 17
August 2025 Keratin – A Very Versatile Protein Question 27
June 2025 Organisms of the Tibetan Plateau Question 18
Nature or Nurture? Question 46
Sample clusters (Spring 2024) Prostaglandins Question 3

Performance Level Descriptions

PLDs communicate the knowledge and skills expected of students to demonstrate proficiency in each Learning Standard. NYS assessments classify student performance into one of five levels.

☐
Level 1: Identify a claim, from those provided, based on evidence that inheritable genetic variation occurs.
☐
Level 2: Identify a claim based on evidence for a cause of inheritable genetic variation.
☐
Level 3: Make or defend a claim based on evidence that inheritable genetic variations may result from: (1) new genetic combinations through meiosis and/or (2) viable errors occurring during replication, and/or (3) mutations caused by environmental factors and/or (4) genetic engineering.
☐
Level 4: Make and defend a claim based on evidence that inheritable genetic variations may result from: (1) new genetic combinations through meiosis, (2) viable errors occurring during replication, (3) mutations caused by environmental factors and/or (4) genetic engineering.
☐
Level 5: Make and defend a claim based on evidence regarding the causes of inheritable genetic variations, which may result from: (1) new genetic combinations through meiosis, (2) viable errors occurring during replication, (3) mutations caused by environmental factors and/or (4) genetic engineering, and the variation's effect.

Vocabulary

Terms from the Biology Glossary that come from this standard or from the released exam questions that assess it.

From this standard
  • argument
  • biotechnology
  • cell
  • chromosome
  • claim
  • correlation (versus cause)
  • DNA replication
  • empirical evidence
  • environmental factor
  • gene
  • genetic combination
  • genetic engineering
  • genetic variation
  • genetically modified
  • inheritable variation
  • meiosis
  • mutation
  • population
  • probability
  • replication error
  • sex cell
  • sexual reproduction
  • trait
  • variation
From released exam questions
Implied by this standard
  • crossing over – implied by "chromosomes can sometimes swap sections during the process of meiosis"

Resources

Examples and discussion of resources for the learning, teaching, and assessment of HS-LS3-2.

Pixel beaver This section could be expanded upon. You can help out by adding to this section.


NGSS Dimensions

Performance expectation HS-LS3-2 was developed using the following elements from the NRC document A Framework for K-12 Science Education:

Science and Engineering Practices
  • Engaging in Argument from Evidence
    • Make and defend a claim based on evidence about the natural world that reflects scientific knowledge, and student-generated evidence.
Disciplinary Core Ideas
  • LS3.B: Variation of Traits
    • In sexual reproduction, chromosomes can sometimes swap sections during the process of meiosis (cell division), thereby creating new genetic combinations and thus more genetic variation. Although DNA replication is tightly regulated and remarkably accurate, errors do occur and result in mutations, which are also a source of genetic variation.
    • (NYSED) Environmental factors can cause mutations in genes. Only mutations in sex cells can be inherited.
    • (NYSED) Advances in biotechnology have allowed organisms to be modified genetically.
    • Environmental factors also affect expression of traits, and hence affect the probability of occurrences of traits in a population. Thus the variation and distribution of traits observed depends on both genetic and environmental factors.
Crosscutting Concepts
  • Cause and Effect
    • Empirical evidence is required to differentiate between cause and correlation to make claims about specific causes and effects.
Page contributors: Conrad Richman, Caroline Leonard
Biology | HS. Inheritance and Variation of Traits
Retrieved from "https://nyssls.info/index.php?title=HS-LS3-2&oldid=5731"

About Us • Privacy Policy • Contact Us • Terms of Use