January 2026 Biology Regents Exam · questions and answer key

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The January 2026 Biology Regents exam (the Regents Examination in Life Science: Biology) has 45 questions, 29 multiple choice and 16 constructed response, organized into ten question clusters. Select a cluster to see its questions with the answer key. Each question is listed with the NYSSLS performance expectation it assesses. Data on the percentage of students answering correctly is not yet available.


Two Kinds of Twins · Questions 1–5

Question Standard % correct
Question 1 HS-LS1-8 —
Question 2 HS-LS1-4 —
Question 3 HS-LS3-2 —
Question 4 HS-LS3-1 —
Question 5 HS-ETS1-2 —



Space Invader · Questions 6–9

Question Standard % correct
Question 6 HS-LS3-1 —
Question 7 HS-LS1-5 —
Question 8 HS-LS2-2 —
Question 9 HS-ETS1-3 —



Keystone Species Rule · Questions 10–13

Question Standard % correct
Question 10 HS-LS2-6 —
Question 11 HS-ESS2-6 —
Question 12 HS-LS2-7 —
Question 13 HS-LS2-8 —

Solving the Problem of Cat Allergies · Questions 14–18

Question Standard % correct
Question 14 HS-LS1-1 —
Question 15 HS-LS1-2 —
Question 16 HS-LS3-3 —
Question 17 HS-LS3-2 —
Question 18 HS-LS1-1 —

A Hard Pest to Manage · Questions 19–22

Question Standard % correct
Question 19 HS-LS4-3 —
Question 20 HS-LS3-1 —
Question 21 HS-LS3-3 —
Question 22 HS-LS4-1 —



Diabetes · Questions 23–27

Question Standard % correct
Question 23 HS-LS1-7 —
Question 24 HS-LS1-2 —
Question 25 HS-LS1-3 —
Question 26 HS-LS1-1 —
Question 27 HS-ETS1-1 —



Honeybee Behavior and Threats · Questions 28–32

Question Standard % correct
Question 28 HS-ETS1-2 —
Question 29 HS-LS2-8 —
Question 30 HS-LS2-2 —
Question 31 HS-LS4-2 —
Question 32 HS-LS2-1 —



Baboon Evolution · Questions 33–36

Question Standard % correct
Question 33 HS-LS4-1 —
Question 34 HS-LS4-2 —
Question 35 HS-LS2-8 —
Question 36 HS-LS4-4 —



Purple Insect Eater · Questions 37–40

Question Standard % correct
Question 37 HS-LS1-5 —
Question 38 HS-ESS2-6 —
Question 39 HS-LS2-3 —
Question 40 HS-LS1-2 —

Zebra Coat Patterns · Questions 41–45

Question Standard % correct
Question 41 HS-LS3-1 —
Question 42 HS-LS1-1 —
Question 43 HS-LS4-2 —
Question 44 HS-LS3-3 —
Question 45 HS-LS2-7 —
Page contributors: Caroline Leonard